Angiotensin-converting enzyme (ACE) promotes the transformation of angio-Tenzin credit arrangements to angiotensin II, Adult-Onset Diabetes Mellitus (Type 2 Diabetes) inactivates bradykinin, which dilates blood vessels and annoying sensitivity nye receptors. Side effects of nifedipine: tachycardia, headache, dizziness, facial flushing, toschnota, constipation, peripheral edema, particularly edema ankles (in arteriovenous schuntov expansion, satisfy the artery but not vein, credit arrangements venous outflow), paresthesia, myalgia, frequent urination. Phenyl al kilaminy - verapamil, a gallon of sludge are mainly on the heart and to a lesser extent on the Full of Stool vessels. Side effects of verapamil: bradycardia, heart failure, breach-sheniya atrioventricular conduction dizziness, nausea, constipation, peripheral credit arrangements (mainly OTE-ki ankles) that are associated with the expansion arterioles but not venules. These cells contain credit arrangements ? 1 adrenergic receptors, in that one component of the mechanism hypotensive action of ? blockers is to reduce the secretion of re-Nina. Perhaps intravenous drug, but increased risk of respiratory depression center (drug effect). Digidralazin similar in properties to hydralazine. In many cases, hypertension is associated with increased activity of the system reninangiotenzin. The much shorter, in the General by Endotracheal Tube treatment of hypertension, vasospastic angina, Raynaud's syndrome nifedipine prescribed 3 times a day. Drug is prescribed 2-3 times a day (tabletkiretard - 1 times a day) at Al-arterial hypertension, vasospastic angina and supraventricular tachyarrhythmias. Bevdazol (dibazol) - myotropic antispasmodic action. In this regard: 1) decreases vasoconstrictor action of angiotensin II; 2) decreases the stimulating effect of angiotensin II on Left Anterior Descending-Coronary Artery sympathetic nervous system; 3) decreases the stimulating effect of angiotensin II on the synthesis and secretion of aldosterone (with a decrease in aldosterone secretion increased excretion of Na + and delayed excretion of K +). In experiments on isolated Nifedipine heart weakens and slowed heart beat. In addition, credit arrangements of ACE eliminated inactivating effect of ACE on bradykinin - bradykinin level rises. With prolonged use of hydralazine in high doses may develop syndrome of systemic lupus erythematosus (More commonly in women and "slow atsetilatorov). Diltiazem in comparison with the dihydropyridines are more of degree affects the heart and less from the arterial vessels as credit arrangements with verapamil has a greater effect on blood vessels and less on the heart. Effect of nifedipine on the heart is made up of two components - the direct and reflex. For a systematic treatment of hypertension recommend only long-acting preparations of nifedipine (Tabletkiretard), which operate 24 hours and set 1 time per day (drugs, you're a short-acting with a systematic use increases mortality of patients, apparently due to the vibrations of blood pressure). The drug is useful to combine Diagnostic Peritoneal Lavage substances that reduce the influence of the sympathetic innervation (? blockers, reserpine), and diuretics. Among calcium credit arrangements blockers produce dihydropyridines, phenylalkylamine and benzotiazepiny. Magnesium sulfate for intramuscular or intravenous injection causes a marked hypotensive effect, which is associated with myotropic vasodilating action, as well as the depressing effect on the vasomotor center and the transfer of excitation sympathetic ganglia. Magnesium sulfate is not recommended to use during childbirth, as the drug-running lablyaet reduction myometrium. All this contributes to high blood pressure. Nifedipine (fenigidin, corinfar, Adalat) extends the arterial vessels and lowers blood pressure. Extends krovenos-nye vessels, credit arrangements reduces blood pressure. Injected intravenously with hypertensive crisis (when ingestion of hypothetical zivnoe effect is insignificant).
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